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<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd">
<html xmlns="http://www.w3.org/1999/xhtml" xml:lang="en" lang="en">
<head>
<title>SIEVE</title>
<meta name="robots" content="index,follow" />
<link rel="stylesheet" type="text/css" href="http://courses.cs.washington.edu/courses/cse512/15sp/style.css"/>
</head>
<body>
<div class='content wider'>
<div class='title'>
<a href="http://courses.cs.washington.edu/courses/cse512/15sp/"><strong>CSE512</strong></a>
Projects
<small>(Spring 2015)</small>
</div>
<br/>
<div class='pub' data-spy="scroll" data-target=".navbar">
<h1 class="title">SIEVE: Statistical Interactive Explorer of Vaccine Efficacy</h1>
<div class="authors">
<a href="https://github.com/nkullman">Nick Kullman</a>,
<a href="https://github.com/gclenaghan">Graham Clenaghan</a>
<a href="https://github.com/waynefanyang">Wayne Yang</a>
</div>
<div class="figure">
<img src="images/summary.png" width="100%"/>
<div class="caption">An overview of the interface to SIEVE</div>
</div>
<p>
SIEVE is an interactive visualization for exploring data from vaccine studies.
Specifically, we aim to aid the process of sieve analysis, which compares the genetic sequences of viruses found in infected patients between vaccine and placebo groups.
The visualization allows researchers in the field to study the affect of a vaccine at the level of the amino acids in the breakthrough viruses, and find statistically significant differences in the groups.
This work was done in collaboration with Andrew Gartland and Allan DeCamp at Fred Hutch.
</p>
<h2>Software</h2>
<p>
Try it online <a href="https://cse512-15s.github.io/fp-nkullman-gclenagh-wfyang/main.html">here</a>. Use the help features to get started. The visualization uses data from the RV144 HIV study, specifically the Env protein.
origin/gh-pages
</p>
<h2>Materials</h2>
<div class="links">
<a href="final/poster-nkullman-gclenagh-wfyang.pdf" >Poster</a>
<a href="final/paper-nkullman-gclenagh-wfyang.pdf" >Paper</a>
<a href="https://github.com/CSE512-15S/fp-nkullman-gclenagh-wfyang/">Code</a>
</div>
<div class='footer'>
<a href='http://cs.washington.edu'>Computer Science & Engineering</a> -
<a href='http://www.washington.edu'>University of Washington</a>
</div>
</div>
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<br/>
</div>
</body>
</html>