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DESCRIPTION
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Package: LUCIDus
Title: LUCID with Multiple Omics Data
Version: 3.1.0
Authors@R: c(
person("Qiran", "Jia", , "qiranjia@usc.edu", role = c("aut", "cre"),
comment = c(ORCID = "0000-0002-0790-5967")),
person(given = "Yinqi", family = "Zhao",
email = "yinqiz@usc.edu",
role = "aut",
comment = c(ORCID = "0000-0003-2413-732X")),
person(given = "David", family = "Conti",
email = "dconti@usc.med.edu", role = "ths",
comment = c(ORCID = "0000-0002-2941-7833")),
person(given = "Jesse", family = "Goodrich",
role = "ctb",
comment = c(ORCID = "0000-0001-6615-0472"))
)
Description: Implements Latent Unknown Clusters By Integrating Multi-omics Data
(LUCID; Peng (2019) <doi:10.1093/bioinformatics/btz667>) for integrative
clustering with exposures, multi-omics data, and health outcomes.
Supports three integration strategies: early, parallel, and serial.
Provides model fitting and tuning, lasso-type regularization for exposure
and omics feature selection, handling of missing data, including both
sporadic and complete-case patterns, prediction, and g-computation for
estimating causal effects of exposures, bootstrap inference for
uncertainty estimation, and S3 summary and plot methods. For the
multi-omics integration framework, see Jia (2024)
<https://journal.r-project.org/articles/RJ-2024-012/RJ-2024-012.pdf>.
For the missing-data imputation mechanism, see Jia (2024)
<doi:10.1093/bioadv/vbae123>.
Depends: R (>= 3.6.0)
License: MIT + file LICENSE
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.3
LazyData: true
Suggests: testthat (>= 3.0.0)
Config/testthat/edition: 3
Imports: mclust, nnet, boot, jsonlite, networkD3, progress, stats,
utils, glasso, glmnet
URL: https://journal.r-project.org/articles/RJ-2024-012/RJ-2024-012.pdf,
https://doi.org/10.1093/bioadv/vbae123
NeedsCompilation: no
Packaged: 2024-09-23 19:49:22 UTC; qiranjia19961112
Author: Qiran Jia [aut, cre] (<https://orcid.org/0000-0002-0790-5967>),
Yinqi Zhao [aut] (<https://orcid.org/0000-0003-2413-732X>),
David Conti [ths] (<https://orcid.org/0000-0002-2941-7833>),
Jesse Goodrich [ctb] (<https://orcid.org/0000-0001-6615-0472>)
Maintainer: Qiran Jia <qiranjia@usc.edu>