diff --git a/changelog.d/18577.misc b/changelog.d/18577.misc
new file mode 100644
index 00000000000..339591b3204
--- /dev/null
+++ b/changelog.d/18577.misc
@@ -0,0 +1 @@
+Add support for Twisted `25.5.0`+ releases.
\ No newline at end of file
diff --git a/poetry.lock b/poetry.lock
index a9ec91acfa4..8211b096c8d 100644
--- a/poetry.lock
+++ b/poetry.lock
@@ -1,4 +1,4 @@
-# This file is automatically @generated by Poetry 2.1.1 and should not be changed by hand.
+# This file is automatically @generated by Poetry 2.1.3 and should not be changed by hand.
 
 [[package]]
 name = "annotated-types"
@@ -39,7 +39,7 @@ description = "The ultimate Python library in building OAuth and OpenID Connect
 optional = true
 python-versions = ">=3.9"
 groups = ["main"]
-markers = "extra == \"all\" or extra == \"jwt\" or extra == \"oidc\""
+markers = "extra == \"oidc\" or extra == \"jwt\" or extra == \"all\""
 files = [
     {file = "authlib-1.5.2-py2.py3-none-any.whl", hash = "sha256:8804dd4402ac5e4a0435ac49e0b6e19e395357cfa632a3f624dcb4f6df13b4b1"},
     {file = "authlib-1.5.2.tar.gz", hash = "sha256:fe85ec7e50c5f86f1e2603518bb3b4f632985eb4a355e52256530790e326c512"},
@@ -50,19 +50,18 @@ cryptography = "*"
 
 [[package]]
 name = "automat"
-version = "22.10.0"
+version = "25.4.16"
 description = "Self-service finite-state machines for the programmer on the go."
 optional = false
-python-versions = "*"
+python-versions = ">=3.9"
 groups = ["main"]
 files = [
-    {file = "Automat-22.10.0-py2.py3-none-any.whl", hash = "sha256:c3164f8742b9dc440f3682482d32aaff7bb53f71740dd018533f9de286b64180"},
-    {file = "Automat-22.10.0.tar.gz", hash = "sha256:e56beb84edad19dcc11d30e8d9b895f75deeb5ef5e96b84a467066b3b84bb04e"},
+    {file = "automat-25.4.16-py3-none-any.whl", hash = "sha256:04e9bce696a8d5671ee698005af6e5a9fa15354140a87f4870744604dcdd3ba1"},
+    {file = "automat-25.4.16.tar.gz", hash = "sha256:0017591a5477066e90d26b0e696ddc143baafd87b588cfac8100bc6be9634de0"},
 ]
 
 [package.dependencies]
-attrs = ">=19.2.0"
-six = "*"
+typing_extensions = {version = "*", markers = "python_version < \"3.10\""}
 
 [package.extras]
 visualize = ["Twisted (>=16.1.1)", "graphviz (>0.5.1)"]
@@ -451,7 +450,7 @@ description = "XML bomb protection for Python stdlib modules"
 optional = true
 python-versions = ">=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*"
 groups = ["main"]
-markers = "extra == \"all\" or extra == \"saml2\""
+markers = "extra == \"saml2\" or extra == \"all\""
 files = [
     {file = "defusedxml-0.7.1-py2.py3-none-any.whl", hash = "sha256:a352e7e428770286cc899e2542b6cdaedb2b4953ff269a210103ec58f6198a61"},
     {file = "defusedxml-0.7.1.tar.gz", hash = "sha256:1bb3032db185915b62d7c6209c5a8792be6a32ab2fedacc84e01b52c51aa3e69"},
@@ -494,7 +493,7 @@ description = "XPath 1.0/2.0/3.0/3.1 parsers and selectors for ElementTree and l
 optional = true
 python-versions = ">=3.7"
 groups = ["main"]
-markers = "extra == \"all\" or extra == \"saml2\""
+markers = "extra == \"saml2\" or extra == \"all\""
 files = [
     {file = "elementpath-4.1.5-py3-none-any.whl", hash = "sha256:2ac1a2fb31eb22bbbf817f8cf6752f844513216263f0e3892c8e79782fe4bb55"},
     {file = "elementpath-4.1.5.tar.gz", hash = "sha256:c2d6dc524b29ef751ecfc416b0627668119d8812441c555d7471da41d4bacb8d"},
@@ -544,7 +543,7 @@ description = "Python wrapper for hiredis"
 optional = true
 python-versions = ">=3.8"
 groups = ["main"]
-markers = "extra == \"all\" or extra == \"redis\""
+markers = "extra == \"redis\" or extra == \"all\""
 files = [
     {file = "hiredis-3.1.0-cp310-cp310-macosx_10_15_universal2.whl", hash = "sha256:2892db9db21f0cf7cc298d09f85d3e1f6dc4c4c24463ab67f79bc7a006d51867"},
     {file = "hiredis-3.1.0-cp310-cp310-macosx_10_15_x86_64.whl", hash = "sha256:93cfa6cc25ee2ceb0be81dc61eca9995160b9e16bdb7cca4a00607d57e998918"},
@@ -890,7 +889,7 @@ description = "Jaeger Python OpenTracing Tracer implementation"
 optional = true
 python-versions = ">=3.7"
 groups = ["main"]
-markers = "extra == \"all\" or extra == \"opentracing\""
+markers = "extra == \"opentracing\" or extra == \"all\""
 files = [
     {file = "jaeger-client-4.8.0.tar.gz", hash = "sha256:3157836edab8e2c209bd2d6ae61113db36f7ee399e66b1dcbb715d87ab49bfe0"},
 ]
@@ -1028,7 +1027,7 @@ description = "A strictly RFC 4510 conforming LDAP V3 pure Python client library
 optional = true
 python-versions = "*"
 groups = ["main"]
-markers = "extra == \"all\" or extra == \"matrix-synapse-ldap3\""
+markers = "extra == \"matrix-synapse-ldap3\" or extra == \"all\""
 files = [
     {file = "ldap3-2.9.1-py2.py3-none-any.whl", hash = "sha256:5869596fc4948797020d3f03b7939da938778a0f9e2009f7a072ccf92b8e8d70"},
     {file = "ldap3-2.9.1.tar.gz", hash = "sha256:f3e7fc4718e3f09dda568b57100095e0ce58633bcabbed8667ce3f8fbaa4229f"},
@@ -1044,7 +1043,7 @@ description = "Powerful and Pythonic XML processing library combining libxml2/li
 optional = true
 python-versions = ">=3.6"
 groups = ["main"]
-markers = "extra == \"all\" or extra == \"url-preview\""
+markers = "extra == \"url-preview\" or extra == \"all\""
 files = [
     {file = "lxml-5.4.0-cp310-cp310-macosx_10_9_universal2.whl", hash = "sha256:e7bc6df34d42322c5289e37e9971d6ed114e3776b45fa879f734bded9d1fea9c"},
     {file = "lxml-5.4.0-cp310-cp310-macosx_10_9_x86_64.whl", hash = "sha256:6854f8bd8a1536f8a1d9a3655e6354faa6406621cf857dc27b681b69860645c7"},
@@ -1324,7 +1323,7 @@ description = "An LDAP3 auth provider for Synapse"
 optional = true
 python-versions = ">=3.7"
 groups = ["main"]
-markers = "extra == \"all\" or extra == \"matrix-synapse-ldap3\""
+markers = "extra == \"matrix-synapse-ldap3\" or extra == \"all\""
 files = [
     {file = "matrix-synapse-ldap3-0.3.0.tar.gz", hash = "sha256:8bb6517173164d4b9cc44f49de411d8cebdb2e705d5dd1ea1f38733c4a009e1d"},
     {file = "matrix_synapse_ldap3-0.3.0-py3-none-any.whl", hash = "sha256:8b4d701f8702551e98cc1d8c20dbed532de5613584c08d0df22de376ba99159d"},
@@ -1545,7 +1544,7 @@ description = "OpenTracing API for Python. See documentation at http://opentraci
 optional = true
 python-versions = "*"
 groups = ["main"]
-markers = "extra == \"all\" or extra == \"opentracing\""
+markers = "extra == \"opentracing\" or extra == \"all\""
 files = [
     {file = "opentracing-2.4.0.tar.gz", hash = "sha256:a173117e6ef580d55874734d1fa7ecb6f3655160b8b8974a2a1e98e5ec9c840d"},
 ]
@@ -1714,7 +1713,7 @@ description = "psycopg2 - Python-PostgreSQL Database Adapter"
 optional = true
 python-versions = ">=3.8"
 groups = ["main"]
-markers = "extra == \"all\" or extra == \"postgres\""
+markers = "extra == \"postgres\" or extra == \"all\""
 files = [
     {file = "psycopg2-2.9.10-cp310-cp310-win32.whl", hash = "sha256:5df2b672140f95adb453af93a7d669d7a7bf0a56bcd26f1502329166f4a61716"},
     {file = "psycopg2-2.9.10-cp310-cp310-win_amd64.whl", hash = "sha256:c6f7b8561225f9e711a9c47087388a97fdc948211c10a4bccbf0ba68ab7b3b5a"},
@@ -1722,7 +1721,6 @@ files = [
     {file = "psycopg2-2.9.10-cp311-cp311-win_amd64.whl", hash = "sha256:0435034157049f6846e95103bd8f5a668788dd913a7c30162ca9503fdf542cb4"},
     {file = "psycopg2-2.9.10-cp312-cp312-win32.whl", hash = "sha256:65a63d7ab0e067e2cdb3cf266de39663203d38d6a8ed97f5ca0cb315c73fe067"},
     {file = "psycopg2-2.9.10-cp312-cp312-win_amd64.whl", hash = "sha256:4a579d6243da40a7b3182e0430493dbd55950c493d8c68f4eec0b302f6bbf20e"},
-    {file = "psycopg2-2.9.10-cp313-cp313-win_amd64.whl", hash = "sha256:91fd603a2155da8d0cfcdbf8ab24a2d54bca72795b90d2a3ed2b6da8d979dee2"},
     {file = "psycopg2-2.9.10-cp39-cp39-win32.whl", hash = "sha256:9d5b3b94b79a844a986d029eee38998232451119ad653aea42bb9220a8c5066b"},
     {file = "psycopg2-2.9.10-cp39-cp39-win_amd64.whl", hash = "sha256:88138c8dedcbfa96408023ea2b0c369eda40fe5d75002c0964c78f46f11fa442"},
     {file = "psycopg2-2.9.10.tar.gz", hash = "sha256:12ec0b40b0273f95296233e8750441339298e6a572f7039da5b260e3c8b60e11"},
@@ -1735,7 +1733,7 @@ description = ".. image:: https://travis-ci.org/chtd/psycopg2cffi.svg?branch=mas
 optional = true
 python-versions = "*"
 groups = ["main"]
-markers = "platform_python_implementation == \"PyPy\" and (extra == \"all\" or extra == \"postgres\")"
+markers = "platform_python_implementation == \"PyPy\" and (extra == \"postgres\" or extra == \"all\")"
 files = [
     {file = "psycopg2cffi-2.9.0.tar.gz", hash = "sha256:7e272edcd837de3a1d12b62185eb85c45a19feda9e62fa1b120c54f9e8d35c52"},
 ]
@@ -1751,7 +1749,7 @@ description = "A Simple library to enable psycopg2 compatability"
 optional = true
 python-versions = "*"
 groups = ["main"]
-markers = "platform_python_implementation == \"PyPy\" and (extra == \"all\" or extra == \"postgres\")"
+markers = "platform_python_implementation == \"PyPy\" and (extra == \"postgres\" or extra == \"all\")"
 files = [
     {file = "psycopg2cffi-compat-1.1.tar.gz", hash = "sha256:d25e921748475522b33d13420aad5c2831c743227dc1f1f2585e0fdb5c914e05"},
 ]
@@ -1974,7 +1972,7 @@ description = "Python extension wrapping the ICU C++ API"
 optional = true
 python-versions = "*"
 groups = ["main"]
-markers = "extra == \"all\" or extra == \"user-search\""
+markers = "extra == \"user-search\" or extra == \"all\""
 files = [
     {file = "PyICU-2.14.tar.gz", hash = "sha256:acc7eb92bd5c554ed577249c6978450a4feda0aa6f01470152b3a7b382a02132"},
 ]
@@ -2023,7 +2021,7 @@ description = "A development tool to measure, monitor and analyze the memory beh
 optional = true
 python-versions = ">=3.6"
 groups = ["main"]
-markers = "extra == \"all\" or extra == \"cache-memory\""
+markers = "extra == \"cache-memory\" or extra == \"all\""
 files = [
     {file = "Pympler-1.0.1-py3-none-any.whl", hash = "sha256:d260dda9ae781e1eab6ea15bacb84015849833ba5555f141d2d9b7b7473b307d"},
     {file = "Pympler-1.0.1.tar.gz", hash = "sha256:993f1a3599ca3f4fcd7160c7545ad06310c9e12f70174ae7ae8d4e25f6c5d3fa"},
@@ -2083,7 +2081,7 @@ description = "Python implementation of SAML Version 2 Standard"
 optional = true
 python-versions = ">=3.9,<4.0"
 groups = ["main"]
-markers = "extra == \"all\" or extra == \"saml2\""
+markers = "extra == \"saml2\" or extra == \"all\""
 files = [
     {file = "pysaml2-7.5.0-py3-none-any.whl", hash = "sha256:bc6627cc344476a83c757f440a73fda1369f13b6fda1b4e16bca63ffbabb5318"},
     {file = "pysaml2-7.5.0.tar.gz", hash = "sha256:f36871d4e5ee857c6b85532e942550d2cf90ea4ee943d75eb681044bbc4f54f7"},
@@ -2108,7 +2106,7 @@ description = "Extensions to the standard Python datetime module"
 optional = true
 python-versions = "!=3.0.*,!=3.1.*,!=3.2.*,>=2.7"
 groups = ["main"]
-markers = "extra == \"all\" or extra == \"saml2\""
+markers = "extra == \"saml2\" or extra == \"all\""
 files = [
     {file = "python-dateutil-2.8.2.tar.gz", hash = "sha256:0123cacc1627ae19ddf3c27a5de5bd67ee4586fbdd6440d9748f8abb483d3e86"},
     {file = "python_dateutil-2.8.2-py2.py3-none-any.whl", hash = "sha256:961d03dc3453ebbc59dbdea9e4e11c5651520a876d0f4db161e8674aae935da9"},
@@ -2136,7 +2134,7 @@ description = "World timezone definitions, modern and historical"
 optional = true
 python-versions = "*"
 groups = ["main"]
-markers = "extra == \"all\" or extra == \"saml2\""
+markers = "extra == \"saml2\" or extra == \"all\""
 files = [
     {file = "pytz-2022.7.1-py2.py3-none-any.whl", hash = "sha256:78f4f37d8198e0627c5f1143240bb0206b8691d8d7ac6d78fee88b78733f8c4a"},
     {file = "pytz-2022.7.1.tar.gz", hash = "sha256:01a0681c4b9684a28304615eba55d1ab31ae00bf68ec157ec3708a8182dbbcd0"},
@@ -2500,7 +2498,7 @@ description = "Python client for Sentry (https://sentry.io)"
 optional = true
 python-versions = ">=3.6"
 groups = ["main"]
-markers = "extra == \"all\" or extra == \"sentry\""
+markers = "extra == \"sentry\" or extra == \"all\""
 files = [
     {file = "sentry_sdk-2.22.0-py2.py3-none-any.whl", hash = "sha256:3d791d631a6c97aad4da7074081a57073126c69487560c6f8bffcf586461de66"},
     {file = "sentry_sdk-2.22.0.tar.gz", hash = "sha256:b4bf43bb38f547c84b2eadcefbe389b36ef75f3f38253d7a74d6b928c07ae944"},
@@ -2688,7 +2686,7 @@ description = "Tornado IOLoop Backed Concurrent Futures"
 optional = true
 python-versions = "*"
 groups = ["main"]
-markers = "extra == \"all\" or extra == \"opentracing\""
+markers = "extra == \"opentracing\" or extra == \"all\""
 files = [
     {file = "threadloop-1.0.2-py2-none-any.whl", hash = "sha256:5c90dbefab6ffbdba26afb4829d2a9df8275d13ac7dc58dccb0e279992679599"},
     {file = "threadloop-1.0.2.tar.gz", hash = "sha256:8b180aac31013de13c2ad5c834819771992d350267bddb854613ae77ef571944"},
@@ -2704,7 +2702,7 @@ description = "Python bindings for the Apache Thrift RPC system"
 optional = true
 python-versions = "*"
 groups = ["main"]
-markers = "extra == \"all\" or extra == \"opentracing\""
+markers = "extra == \"opentracing\" or extra == \"all\""
 files = [
     {file = "thrift-0.16.0.tar.gz", hash = "sha256:2b5b6488fcded21f9d312aa23c9ff6a0195d0f6ae26ddbd5ad9e3e25dfc14408"},
 ]
@@ -2766,7 +2764,7 @@ description = "Tornado is a Python web framework and asynchronous networking lib
 optional = true
 python-versions = ">=3.9"
 groups = ["main"]
-markers = "extra == \"all\" or extra == \"opentracing\""
+markers = "extra == \"opentracing\" or extra == \"all\""
 files = [
     {file = "tornado-6.5-cp39-abi3-macosx_10_9_universal2.whl", hash = "sha256:f81067dad2e4443b015368b24e802d0083fecada4f0a4572fdb72fc06e54a9a6"},
     {file = "tornado-6.5-cp39-abi3-macosx_10_9_x86_64.whl", hash = "sha256:9ac1cbe1db860b3cbb251e795c701c41d343f06a96049d6274e7c77559117e41"},
@@ -2857,19 +2855,19 @@ keyring = ["keyring (>=15.1)"]
 
 [[package]]
 name = "twisted"
-version = "24.7.0"
+version = "25.5.0"
 description = "An asynchronous networking framework written in Python"
 optional = false
 python-versions = ">=3.8.0"
 groups = ["main"]
 files = [
-    {file = "twisted-24.7.0-py3-none-any.whl", hash = "sha256:734832ef98108136e222b5230075b1079dad8a3fc5637319615619a7725b0c81"},
-    {file = "twisted-24.7.0.tar.gz", hash = "sha256:5a60147f044187a127ec7da96d170d49bcce50c6fd36f594e60f4587eff4d394"},
+    {file = "twisted-25.5.0-py3-none-any.whl", hash = "sha256:8559f654d01a54a8c3efe66d533d43f383531ebf8d81d9f9ab4769d91ca15df7"},
+    {file = "twisted-25.5.0.tar.gz", hash = "sha256:1deb272358cb6be1e3e8fc6f9c8b36f78eb0fa7c2233d2dbe11ec6fee04ea316"},
 ]
 
 [package.dependencies]
-attrs = ">=21.3.0"
-automat = ">=0.8.0"
+attrs = ">=22.2.0"
+automat = ">=24.8.0"
 constantly = ">=15.1"
 hyperlink = ">=17.1.1"
 idna = {version = ">=2.4", optional = true, markers = "extra == \"tls\""}
@@ -2880,19 +2878,20 @@ typing-extensions = ">=4.2.0"
 zope-interface = ">=5"
 
 [package.extras]
-all-non-platform = ["appdirs (>=1.4.0)", "appdirs (>=1.4.0)", "bcrypt (>=3.1.3)", "bcrypt (>=3.1.3)", "cryptography (>=3.3)", "cryptography (>=3.3)", "cython-test-exception-raiser (>=1.0.2,<2)", "cython-test-exception-raiser (>=1.0.2,<2)", "h2 (>=3.0,<5.0)", "h2 (>=3.0,<5.0)", "hypothesis (>=6.56)", "hypothesis (>=6.56)", "idna (>=2.4)", "idna (>=2.4)", "priority (>=1.1.0,<2.0)", "priority (>=1.1.0,<2.0)", "pyhamcrest (>=2)", "pyhamcrest (>=2)", "pyopenssl (>=21.0.0)", "pyopenssl (>=21.0.0)", "pyserial (>=3.0)", "pyserial (>=3.0)", "pywin32 (!=226) ; platform_system == \"Windows\"", "pywin32 (!=226) ; platform_system == \"Windows\"", "service-identity (>=18.1.0)", "service-identity (>=18.1.0)"]
+all-non-platform = ["appdirs (>=1.4.0)", "appdirs (>=1.4.0)", "bcrypt (>=3.1.3)", "bcrypt (>=3.1.3)", "cryptography (>=3.3)", "cryptography (>=3.3)", "cython-test-exception-raiser (>=1.0.2,<2)", "cython-test-exception-raiser (>=1.0.2,<2)", "h2 (>=3.2,<5.0)", "h2 (>=3.2,<5.0)", "httpx[http2] (>=0.27)", "httpx[http2] (>=0.27)", "hypothesis (>=6.56)", "hypothesis (>=6.56)", "idna (>=2.4)", "idna (>=2.4)", "priority (>=1.1.0,<2.0)", "priority (>=1.1.0,<2.0)", "pyhamcrest (>=2)", "pyhamcrest (>=2)", "pyopenssl (>=21.0.0)", "pyopenssl (>=21.0.0)", "pyserial (>=3.0)", "pyserial (>=3.0)", "pywin32 (!=226) ; platform_system == \"Windows\"", "pywin32 (!=226) ; platform_system == \"Windows\"", "service-identity (>=18.1.0)", "service-identity (>=18.1.0)", "wsproto", "wsproto"]
 conch = ["appdirs (>=1.4.0)", "bcrypt (>=3.1.3)", "cryptography (>=3.3)"]
-dev = ["coverage (>=7.5,<8.0)", "cython-test-exception-raiser (>=1.0.2,<2)", "hypothesis (>=6.56)", "pydoctor (>=23.9.0,<23.10.0)", "pyflakes (>=2.2,<3.0)", "pyhamcrest (>=2)", "python-subunit (>=1.4,<2.0)", "sphinx (>=6,<7)", "sphinx-rtd-theme (>=1.3,<2.0)", "towncrier (>=23.6,<24.0)", "twistedchecker (>=0.7,<1.0)"]
-dev-release = ["pydoctor (>=23.9.0,<23.10.0)", "pydoctor (>=23.9.0,<23.10.0)", "sphinx (>=6,<7)", "sphinx (>=6,<7)", "sphinx-rtd-theme (>=1.3,<2.0)", "sphinx-rtd-theme (>=1.3,<2.0)", "towncrier (>=23.6,<24.0)", "towncrier (>=23.6,<24.0)"]
-gtk-platform = ["appdirs (>=1.4.0)", "appdirs (>=1.4.0)", "bcrypt (>=3.1.3)", "bcrypt (>=3.1.3)", "cryptography (>=3.3)", "cryptography (>=3.3)", "cython-test-exception-raiser (>=1.0.2,<2)", "cython-test-exception-raiser (>=1.0.2,<2)", "h2 (>=3.0,<5.0)", "h2 (>=3.0,<5.0)", "hypothesis (>=6.56)", "hypothesis (>=6.56)", "idna (>=2.4)", "idna (>=2.4)", "priority (>=1.1.0,<2.0)", "priority (>=1.1.0,<2.0)", "pygobject", "pygobject", "pyhamcrest (>=2)", "pyhamcrest (>=2)", "pyopenssl (>=21.0.0)", "pyopenssl (>=21.0.0)", "pyserial (>=3.0)", "pyserial (>=3.0)", "pywin32 (!=226) ; platform_system == \"Windows\"", "pywin32 (!=226) ; platform_system == \"Windows\"", "service-identity (>=18.1.0)", "service-identity (>=18.1.0)"]
-http2 = ["h2 (>=3.0,<5.0)", "priority (>=1.1.0,<2.0)"]
-macos-platform = ["appdirs (>=1.4.0)", "appdirs (>=1.4.0)", "bcrypt (>=3.1.3)", "bcrypt (>=3.1.3)", "cryptography (>=3.3)", "cryptography (>=3.3)", "cython-test-exception-raiser (>=1.0.2,<2)", "cython-test-exception-raiser (>=1.0.2,<2)", "h2 (>=3.0,<5.0)", "h2 (>=3.0,<5.0)", "hypothesis (>=6.56)", "hypothesis (>=6.56)", "idna (>=2.4)", "idna (>=2.4)", "priority (>=1.1.0,<2.0)", "priority (>=1.1.0,<2.0)", "pyhamcrest (>=2)", "pyhamcrest (>=2)", "pyobjc-core", "pyobjc-core", "pyobjc-framework-cfnetwork", "pyobjc-framework-cfnetwork", "pyobjc-framework-cocoa", "pyobjc-framework-cocoa", "pyopenssl (>=21.0.0)", "pyopenssl (>=21.0.0)", "pyserial (>=3.0)", "pyserial (>=3.0)", "pywin32 (!=226) ; platform_system == \"Windows\"", "pywin32 (!=226) ; platform_system == \"Windows\"", "service-identity (>=18.1.0)", "service-identity (>=18.1.0)"]
-mypy = ["appdirs (>=1.4.0)", "bcrypt (>=3.1.3)", "coverage (>=7.5,<8.0)", "cryptography (>=3.3)", "cython-test-exception-raiser (>=1.0.2,<2)", "h2 (>=3.0,<5.0)", "hypothesis (>=6.56)", "idna (>=2.4)", "mypy (>=1.8,<2.0)", "mypy-zope (>=1.0.3,<1.1.0)", "priority (>=1.1.0,<2.0)", "pydoctor (>=23.9.0,<23.10.0)", "pyflakes (>=2.2,<3.0)", "pyhamcrest (>=2)", "pyopenssl (>=21.0.0)", "pyserial (>=3.0)", "python-subunit (>=1.4,<2.0)", "pywin32 (!=226) ; platform_system == \"Windows\"", "service-identity (>=18.1.0)", "sphinx (>=6,<7)", "sphinx-rtd-theme (>=1.3,<2.0)", "towncrier (>=23.6,<24.0)", "twistedchecker (>=0.7,<1.0)", "types-pyopenssl", "types-setuptools"]
-osx-platform = ["appdirs (>=1.4.0)", "appdirs (>=1.4.0)", "bcrypt (>=3.1.3)", "bcrypt (>=3.1.3)", "cryptography (>=3.3)", "cryptography (>=3.3)", "cython-test-exception-raiser (>=1.0.2,<2)", "cython-test-exception-raiser (>=1.0.2,<2)", "h2 (>=3.0,<5.0)", "h2 (>=3.0,<5.0)", "hypothesis (>=6.56)", "hypothesis (>=6.56)", "idna (>=2.4)", "idna (>=2.4)", "priority (>=1.1.0,<2.0)", "priority (>=1.1.0,<2.0)", "pyhamcrest (>=2)", "pyhamcrest (>=2)", "pyobjc-core", "pyobjc-core", "pyobjc-framework-cfnetwork", "pyobjc-framework-cfnetwork", "pyobjc-framework-cocoa", "pyobjc-framework-cocoa", "pyopenssl (>=21.0.0)", "pyopenssl (>=21.0.0)", "pyserial (>=3.0)", "pyserial (>=3.0)", "pywin32 (!=226) ; platform_system == \"Windows\"", "pywin32 (!=226) ; platform_system == \"Windows\"", "service-identity (>=18.1.0)", "service-identity (>=18.1.0)"]
+dev = ["coverage (>=7.5,<8.0)", "cython-test-exception-raiser (>=1.0.2,<2)", "httpx[http2] (>=0.27)", "hypothesis (>=6.56)", "pydoctor (>=24.11.1,<24.12.0)", "pyflakes (>=2.2,<3.0)", "pyhamcrest (>=2)", "python-subunit (>=1.4,<2.0)", "sphinx (>=6,<7)", "sphinx-rtd-theme (>=1.3,<2.0)", "towncrier (>=23.6,<24.0)", "twistedchecker (>=0.7,<1.0)"]
+dev-release = ["pydoctor (>=24.11.1,<24.12.0)", "pydoctor (>=24.11.1,<24.12.0)", "sphinx (>=6,<7)", "sphinx (>=6,<7)", "sphinx-rtd-theme (>=1.3,<2.0)", "sphinx-rtd-theme (>=1.3,<2.0)", "towncrier (>=23.6,<24.0)", "towncrier (>=23.6,<24.0)"]
+gtk-platform = ["appdirs (>=1.4.0)", "appdirs (>=1.4.0)", "bcrypt (>=3.1.3)", "bcrypt (>=3.1.3)", "cryptography (>=3.3)", "cryptography (>=3.3)", "cython-test-exception-raiser (>=1.0.2,<2)", "cython-test-exception-raiser (>=1.0.2,<2)", "h2 (>=3.2,<5.0)", "h2 (>=3.2,<5.0)", "httpx[http2] (>=0.27)", "httpx[http2] (>=0.27)", "hypothesis (>=6.56)", "hypothesis (>=6.56)", "idna (>=2.4)", "idna (>=2.4)", "priority (>=1.1.0,<2.0)", "priority (>=1.1.0,<2.0)", "pygobject", "pygobject", "pyhamcrest (>=2)", "pyhamcrest (>=2)", "pyopenssl (>=21.0.0)", "pyopenssl (>=21.0.0)", "pyserial (>=3.0)", "pyserial (>=3.0)", "pywin32 (!=226) ; platform_system == \"Windows\"", "pywin32 (!=226) ; platform_system == \"Windows\"", "service-identity (>=18.1.0)", "service-identity (>=18.1.0)", "wsproto", "wsproto"]
+http2 = ["h2 (>=3.2,<5.0)", "priority (>=1.1.0,<2.0)"]
+macos-platform = ["appdirs (>=1.4.0)", "appdirs (>=1.4.0)", "bcrypt (>=3.1.3)", "bcrypt (>=3.1.3)", "cryptography (>=3.3)", "cryptography (>=3.3)", "cython-test-exception-raiser (>=1.0.2,<2)", "cython-test-exception-raiser (>=1.0.2,<2)", "h2 (>=3.2,<5.0)", "h2 (>=3.2,<5.0)", "httpx[http2] (>=0.27)", "httpx[http2] (>=0.27)", "hypothesis (>=6.56)", "hypothesis (>=6.56)", "idna (>=2.4)", "idna (>=2.4)", "priority (>=1.1.0,<2.0)", "priority (>=1.1.0,<2.0)", "pyhamcrest (>=2)", "pyhamcrest (>=2)", "pyobjc-core (<11) ; python_version < \"3.9\"", "pyobjc-core (<11) ; python_version < \"3.9\"", "pyobjc-core ; python_version >= \"3.9\"", "pyobjc-core ; python_version >= \"3.9\"", "pyobjc-framework-cfnetwork (<11) ; python_version < \"3.9\"", "pyobjc-framework-cfnetwork (<11) ; python_version < \"3.9\"", "pyobjc-framework-cfnetwork ; python_version >= \"3.9\"", "pyobjc-framework-cfnetwork ; python_version >= \"3.9\"", "pyobjc-framework-cocoa (<11) ; python_version < \"3.9\"", "pyobjc-framework-cocoa (<11) ; python_version < \"3.9\"", "pyobjc-framework-cocoa ; python_version >= \"3.9\"", "pyobjc-framework-cocoa ; python_version >= \"3.9\"", "pyopenssl (>=21.0.0)", "pyopenssl (>=21.0.0)", "pyserial (>=3.0)", "pyserial (>=3.0)", "pywin32 (!=226) ; platform_system == \"Windows\"", "pywin32 (!=226) ; platform_system == \"Windows\"", "service-identity (>=18.1.0)", "service-identity (>=18.1.0)", "wsproto", "wsproto"]
+mypy = ["appdirs (>=1.4.0)", "bcrypt (>=3.1.3)", "coverage (>=7.5,<8.0)", "cryptography (>=3.3)", "cython-test-exception-raiser (>=1.0.2,<2)", "h2 (>=3.2,<5.0)", "httpx[http2] (>=0.27)", "hypothesis (>=6.56)", "idna (>=2.4)", "mypy (==1.10.1)", "mypy-zope (==1.0.6)", "priority (>=1.1.0,<2.0)", "pydoctor (>=24.11.1,<24.12.0)", "pyflakes (>=2.2,<3.0)", "pyhamcrest (>=2)", "pyopenssl (>=21.0.0)", "pyserial (>=3.0)", "python-subunit (>=1.4,<2.0)", "pywin32 (!=226) ; platform_system == \"Windows\"", "service-identity (>=18.1.0)", "sphinx (>=6,<7)", "sphinx-rtd-theme (>=1.3,<2.0)", "towncrier (>=23.6,<24.0)", "twistedchecker (>=0.7,<1.0)", "types-pyopenssl", "types-setuptools", "wsproto"]
+osx-platform = ["appdirs (>=1.4.0)", "appdirs (>=1.4.0)", "bcrypt (>=3.1.3)", "bcrypt (>=3.1.3)", "cryptography (>=3.3)", "cryptography (>=3.3)", "cython-test-exception-raiser (>=1.0.2,<2)", "cython-test-exception-raiser (>=1.0.2,<2)", "h2 (>=3.2,<5.0)", "h2 (>=3.2,<5.0)", "httpx[http2] (>=0.27)", "httpx[http2] (>=0.27)", "hypothesis (>=6.56)", "hypothesis (>=6.56)", "idna (>=2.4)", "idna (>=2.4)", "priority (>=1.1.0,<2.0)", "priority (>=1.1.0,<2.0)", "pyhamcrest (>=2)", "pyhamcrest (>=2)", "pyobjc-core (<11) ; python_version < \"3.9\"", "pyobjc-core (<11) ; python_version < \"3.9\"", "pyobjc-core ; python_version >= \"3.9\"", "pyobjc-core ; python_version >= \"3.9\"", "pyobjc-framework-cfnetwork (<11) ; python_version < \"3.9\"", "pyobjc-framework-cfnetwork (<11) ; python_version < \"3.9\"", "pyobjc-framework-cfnetwork ; python_version >= \"3.9\"", "pyobjc-framework-cfnetwork ; python_version >= \"3.9\"", "pyobjc-framework-cocoa (<11) ; python_version < \"3.9\"", "pyobjc-framework-cocoa (<11) ; python_version < \"3.9\"", "pyobjc-framework-cocoa ; python_version >= \"3.9\"", "pyobjc-framework-cocoa ; python_version >= \"3.9\"", "pyopenssl (>=21.0.0)", "pyopenssl (>=21.0.0)", "pyserial (>=3.0)", "pyserial (>=3.0)", "pywin32 (!=226) ; platform_system == \"Windows\"", "pywin32 (!=226) ; platform_system == \"Windows\"", "service-identity (>=18.1.0)", "service-identity (>=18.1.0)", "wsproto", "wsproto"]
 serial = ["pyserial (>=3.0)", "pywin32 (!=226) ; platform_system == \"Windows\""]
-test = ["cython-test-exception-raiser (>=1.0.2,<2)", "hypothesis (>=6.56)", "pyhamcrest (>=2)"]
+test = ["cython-test-exception-raiser (>=1.0.2,<2)", "httpx[http2] (>=0.27)", "hypothesis (>=6.56)", "pyhamcrest (>=2)"]
 tls = ["idna (>=2.4)", "pyopenssl (>=21.0.0)", "service-identity (>=18.1.0)"]
-windows-platform = ["appdirs (>=1.4.0)", "appdirs (>=1.4.0)", "bcrypt (>=3.1.3)", "bcrypt (>=3.1.3)", "cryptography (>=3.3)", "cryptography (>=3.3)", "cython-test-exception-raiser (>=1.0.2,<2)", "cython-test-exception-raiser (>=1.0.2,<2)", "h2 (>=3.0,<5.0)", "h2 (>=3.0,<5.0)", "hypothesis (>=6.56)", "hypothesis (>=6.56)", "idna (>=2.4)", "idna (>=2.4)", "priority (>=1.1.0,<2.0)", "priority (>=1.1.0,<2.0)", "pyhamcrest (>=2)", "pyhamcrest (>=2)", "pyopenssl (>=21.0.0)", "pyopenssl (>=21.0.0)", "pyserial (>=3.0)", "pyserial (>=3.0)", "pywin32 (!=226)", "pywin32 (!=226)", "pywin32 (!=226) ; platform_system == \"Windows\"", "pywin32 (!=226) ; platform_system == \"Windows\"", "service-identity (>=18.1.0)", "service-identity (>=18.1.0)", "twisted-iocpsupport (>=1.0.2)", "twisted-iocpsupport (>=1.0.2)"]
+websocket = ["wsproto"]
+windows-platform = ["appdirs (>=1.4.0)", "appdirs (>=1.4.0)", "bcrypt (>=3.1.3)", "bcrypt (>=3.1.3)", "cryptography (>=3.3)", "cryptography (>=3.3)", "cython-test-exception-raiser (>=1.0.2,<2)", "cython-test-exception-raiser (>=1.0.2,<2)", "h2 (>=3.2,<5.0)", "h2 (>=3.2,<5.0)", "httpx[http2] (>=0.27)", "httpx[http2] (>=0.27)", "hypothesis (>=6.56)", "hypothesis (>=6.56)", "idna (>=2.4)", "idna (>=2.4)", "priority (>=1.1.0,<2.0)", "priority (>=1.1.0,<2.0)", "pyhamcrest (>=2)", "pyhamcrest (>=2)", "pyopenssl (>=21.0.0)", "pyopenssl (>=21.0.0)", "pyserial (>=3.0)", "pyserial (>=3.0)", "pywin32 (!=226)", "pywin32 (!=226)", "pywin32 (!=226) ; platform_system == \"Windows\"", "pywin32 (!=226) ; platform_system == \"Windows\"", "service-identity (>=18.1.0)", "service-identity (>=18.1.0)", "twisted-iocpsupport (>=1.0.2)", "twisted-iocpsupport (>=1.0.2)", "wsproto", "wsproto"]
 
 [[package]]
 name = "txredisapi"
@@ -2901,7 +2900,7 @@ description = "non-blocking redis client for python"
 optional = true
 python-versions = "*"
 groups = ["main"]
-markers = "extra == \"all\" or extra == \"redis\""
+markers = "extra == \"redis\" or extra == \"all\""
 files = [
     {file = "txredisapi-1.4.11-py3-none-any.whl", hash = "sha256:ac64d7a9342b58edca13ef267d4fa7637c1aa63f8595e066801c1e8b56b22d0b"},
     {file = "txredisapi-1.4.11.tar.gz", hash = "sha256:3eb1af99aefdefb59eb877b1dd08861efad60915e30ad5bf3d5bf6c5cedcdbc6"},
@@ -3244,7 +3243,7 @@ description = "An XML Schema validator and decoder"
 optional = true
 python-versions = ">=3.7"
 groups = ["main"]
-markers = "extra == \"all\" or extra == \"saml2\""
+markers = "extra == \"saml2\" or extra == \"all\""
 files = [
     {file = "xmlschema-2.4.0-py3-none-any.whl", hash = "sha256:dc87be0caaa61f42649899189aab2fd8e0d567f2cf548433ba7b79278d231a4a"},
     {file = "xmlschema-2.4.0.tar.gz", hash = "sha256:d74cd0c10866ac609e1ef94a5a69b018ad16e39077bc6393408b40c6babee793"},
diff --git a/synapse/http/proxyagent.py b/synapse/http/proxyagent.py
index 68171990351..6217f9b0b20 100644
--- a/synapse/http/proxyagent.py
+++ b/synapse/http/proxyagent.py
@@ -21,7 +21,7 @@
 import logging
 import random
 import re
-from typing import Any, Collection, Dict, List, Optional, Sequence, Tuple, Union
+from typing import Any, Collection, Dict, List, Optional, Sequence, Tuple, Union, cast
 from urllib.parse import urlparse
 from urllib.request import (  # type: ignore[attr-defined]
     getproxies_environment,
@@ -40,6 +40,7 @@
     IProtocol,
     IProtocolFactory,
     IReactorCore,
+    IReactorTime,
     IStreamClientEndpoint,
 )
 from twisted.python.failure import Failure
@@ -129,7 +130,9 @@ def __init__(
     ):
         contextFactory = contextFactory or BrowserLikePolicyForHTTPS()
 
-        _AgentBase.__init__(self, reactor, pool)
+        # `_AgentBase` expects an `IReactorTime` provider. `IReactorCore`
+        # extends `IReactorTime`, so this cast is safe.
+        _AgentBase.__init__(self, cast(IReactorTime, reactor), pool)
 
         if proxy_reactor is None:
             self.proxy_reactor = reactor
@@ -168,7 +171,7 @@ def __init__(
         self.no_proxy = no_proxy
 
         self._policy_for_https = contextFactory
-        self._reactor = reactor
+        self._reactor = cast(IReactorTime, reactor)
 
         self._federation_proxy_endpoint: Optional[IStreamClientEndpoint] = None
         self._federation_proxy_credentials: Optional[ProxyCredentials] = None
@@ -257,7 +260,11 @@ def request(
             raise ValueError(f"Invalid URI {uri!r}")
 
         parsed_uri = URI.fromBytes(uri)
-        pool_key = f"{parsed_uri.scheme!r}{parsed_uri.host!r}{parsed_uri.port}"
+        pool_key: tuple[bytes, bytes, int] = (
+            parsed_uri.scheme,
+            parsed_uri.host,
+            parsed_uri.port,
+        )
         request_path = parsed_uri.originForm
 
         should_skip_proxy = False
@@ -283,7 +290,7 @@ def request(
                 )
             # Cache *all* connections under the same key, since we are only
             # connecting to a single destination, the proxy:
-            pool_key = "http-proxy"
+            pool_key = (b"http-proxy", b"", 0)
             endpoint = self.http_proxy_endpoint
             request_path = uri
         elif (
diff --git a/synapse/http/replicationagent.py b/synapse/http/replicationagent.py
index 4eabbc8af95..d70575dbd5f 100644
--- a/synapse/http/replicationagent.py
+++ b/synapse/http/replicationagent.py
@@ -180,9 +180,16 @@ def request(
         worker_name = parsedURI.netloc.decode("utf-8")
         key_scheme = self._endpointFactory.instance_map[worker_name].scheme()
         key_netloc = self._endpointFactory.instance_map[worker_name].netloc()
-        # This sets the Pool key to be:
-        #  (http(s), <host:port>) or (unix, <socket_path>)
-        key = (key_scheme, key_netloc)
+        # Build a connection pool key.
+        #
+        # `_AgentBase` expects this to be a three-tuple of `(scheme, host,
+        # port)` of type `bytes`. We don't have a real port when connecting via
+        # a Unix socket, so use `0`.
+        key = (
+            key_scheme.encode("ascii"),
+            key_netloc.encode("utf-8"),
+            0,
+        )
 
         # _requestWithEndpoint comes from _AgentBase class
         return self._requestWithEndpoint(
diff --git a/synapse/http/server.py b/synapse/http/server.py
index 8bebafc18e2..311e21774f3 100644
--- a/synapse/http/server.py
+++ b/synapse/http/server.py
@@ -497,7 +497,7 @@ def _get_handler_for_request(
             key word arguments to pass to the callback
         """
         # At this point the path must be bytes.
-        request_path_bytes: bytes = request.path  # type: ignore
+        request_path_bytes: bytes = request.path
         request_path = request_path_bytes.decode("ascii")
         # Treat HEAD requests as GET requests.
         request_method = request.method
diff --git a/tests/logging/test_terse_json.py b/tests/logging/test_terse_json.py
index 33b94cf9fa3..d9cbbbd51ef 100644
--- a/tests/logging/test_terse_json.py
+++ b/tests/logging/test_terse_json.py
@@ -160,7 +160,14 @@ def test_with_request_context(self) -> None:
         logger = self.get_logger(handler)
 
         # A full request isn't needed here.
-        site = Mock(spec=["site_tag", "server_version_string", "getResourceFor"])
+        site = Mock(
+            spec=[
+                "site_tag",
+                "server_version_string",
+                "getResourceFor",
+                "_parsePOSTFormSubmission",
+            ]
+        )
         site.site_tag = "test-site"
         site.server_version_string = "Server v1"
         site.reactor = Mock()
diff --git a/tests/replication/_base.py b/tests/replication/_base.py
index 8437da1cdde..75a36303c9d 100644
--- a/tests/replication/_base.py
+++ b/tests/replication/_base.py
@@ -220,7 +220,7 @@ def assert_request_is_get_repl_stream_updates(
         fetching updates for given stream.
         """
 
-        path: bytes = request.path  # type: ignore
+        path: bytes = request.path
         self.assertRegex(
             path,
             rb"^/_synapse/replication/get_repl_stream_updates/%s/[^/]+$"
diff --git a/tests/server.py b/tests/server.py
index f01708b77fc..0c519bc4c98 100644
--- a/tests/server.py
+++ b/tests/server.py
@@ -343,6 +343,8 @@ def __init__(
         self,
         resource: IResource,
         reactor: IReactorTime,
+        *,
+        parsePOSTFormSubmission: bool = True,
     ):
         """
 
@@ -351,6 +353,7 @@ def __init__(
         """
         self._resource = resource
         self.reactor = reactor
+        self._parsePOSTFormSubmission = parsePOSTFormSubmission
 
     def getResourceFor(self, request: Request) -> IResource:
         return self._resource
@@ -514,9 +517,13 @@ def getHostByName(
 
             tls._get_default_clock = lambda: self
 
-        self.nameResolver = SimpleResolverComplexifier(FakeResolver())
         super().__init__()
 
+        # Override the default name resolver with our fake resolver. This must
+        # happen after `super().__init__()` so that the base class doesn't
+        # overwrite it again.
+        self.nameResolver = SimpleResolverComplexifier(FakeResolver())
+
     def installNameResolver(self, resolver: IHostnameResolver) -> IHostnameResolver:
         raise NotImplementedError()
 
diff --git a/tests/storage/databases/main/test_events_worker.py b/tests/storage/databases/main/test_events_worker.py
index 104d141a72e..18039a07e20 100644
--- a/tests/storage/databases/main/test_events_worker.py
+++ b/tests/storage/databases/main/test_events_worker.py
@@ -449,24 +449,29 @@ def test_failure(self) -> None:
 
     def test_recovery(self) -> None:
         """Test that event fetchers recover after a database outage."""
-        with self._outage():
-            # Kick off a bunch of event fetches but do not pump the reactor
-            event_deferreds = []
-            for event_id in self.event_ids:
-                event_deferreds.append(ensureDeferred(self.store.get_event(event_id)))
-
-            # We should have maxed out on event fetcher threads
-            self.assertEqual(self.store._event_fetch_ongoing, EVENT_QUEUE_THREADS)
-
-            # All the event fetchers will fail
-            self.pump()
-            self.assertEqual(self.store._event_fetch_ongoing, 0)
-
-            for event_deferred in event_deferreds:
-                failure = self.get_failure(event_deferred, Exception)
-                self.assertEqual(
-                    str(failure.value), "Could not connect to the database."
-                )
+        with self.assertLogs(
+            "synapse.metrics.background_process_metrics", level="ERROR"
+        ):
+            with self._outage():
+                # Kick off a bunch of event fetches but do not pump the reactor
+                event_deferreds = []
+                for event_id in self.event_ids:
+                    event_deferreds.append(
+                        ensureDeferred(self.store.get_event(event_id))
+                    )
+
+                # We should have maxed out on event fetcher threads
+                self.assertEqual(self.store._event_fetch_ongoing, EVENT_QUEUE_THREADS)
+
+                # All the event fetchers will fail
+                self.pump()
+                self.assertEqual(self.store._event_fetch_ongoing, 0)
+
+                for event_deferred in event_deferreds:
+                    failure = self.get_failure(event_deferred, Exception)
+                    self.assertEqual(
+                        str(failure.value), "Could not connect to the database."
+                    )
 
         # This next event fetch should succeed
         self.get_success(self.store.get_event(self.event_ids[0]))
diff --git a/tests/test_server.py b/tests/test_server.py
index 9cb6766b5fc..9ebfbf96e7b 100644
--- a/tests/test_server.py
+++ b/tests/test_server.py
@@ -226,8 +226,7 @@ class DummyResource(Resource):
             isLeaf = True
 
             def render(self, request: SynapseRequest) -> bytes:
-                # Type-ignore: mypy thinks request.path is Optional[Any], not bytes.
-                return request.path  # type: ignore[return-value]
+                return request.path
 
         # Setup a resource with some children.
         self.resource = OptionsResource()