You signed in with another tab or window. Reload to refresh your session.You signed out in another tab or window. Reload to refresh your session.You switched accounts on another tab or window. Reload to refresh your session.Dismiss alert
**ChiRAViz** is a visualization tool for exploring *chimeric read alignments* using datasets produced by the ChiRA tool, typically in `chira.sqlite` format.
27
+
28
+
This visualization enables researchers to interactively examine structural variations, fusion transcripts, and other chimeric events identified from RNA-seq data.
29
+
30
+
## How to Use
31
+
32
+
1. **Input Dataset**: Select a dataset in `chira.sqlite` format. This should be generated using the ChiRA tool from RNA sequencing data.
33
+
2. **Visualization**: Once the dataset is loaded, you can:
34
+
- Navigate through detected chimeric junctions.
35
+
- Inspect fusion evidence, read alignments, and relevant gene annotations.
36
+
- Interact with graphical views to zoom, filter, and highlight key features.
37
+
38
+
## Features
39
+
40
+
- **Interactive Graphs**: Explore chimeric junctions in detail with responsive plots.
41
+
- **Gene Annotations**: Visual cues help correlate fusion sites with gene models.
42
+
- **Efficient Performance**: Supports large datasets with client-side rendering.
43
+
44
+
## Requirements
45
+
46
+
Ensure the input dataset has the `.chira.sqlite` extension and includes all necessary metadata from a successful ChiRA analysis run.
47
+
48
+
---
49
+
50
+
For more information on the ChiRA pipeline take a look at:
0 commit comments