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This folder contains an ipython notebook file VWF73_pipeline.ipynb that gives an overview of the high throughput sequencing analysis done for the following manuscript:

"Exosite interactions are required for ADAMTS13 substrate recognition"

Colin A. Kretz*, Kärt Tomberg*, Alexander Van Esbroeck, Andrew Yee, and David Ginsburg

* Shared first authorship

It contains:

  • Information about raw fastq file location
  • All in-house developed scripts for read mapping, filtering, and translation
  • DESEQ2 analysis for significantly enriched peptides