Prenatal human skin morphogenesis is regulated by crosstalk between immune and non-immune cells

This repository contains the data processing and analysis scripts for fetal skin study

Repository contents

• analysis contains scripts and notebooks used for data processing of raw sequencing data
• figures contains scripts and notebooks used for figure generation

Data Availability

Web portal

Processed data can be accessed on our web portal at https://developmental.cellatlas.io/fetal-skin

Raw sequencing data

Raw sequencing libraries for this study are deposited in ArrayExpress

• scRNA-seq libraries:
  • ArrayExpress E-MTAB-13071
  • ArrayExpress E-MTAB-11343 (Suo, Dann et al. 2022)
  • ArrayExpress E-MTAB-7407 (Popescu et al. 2019)
• TCR-seq libraries:
  • ArrayExpress E-MTAB-13065
• Visium libraries:
  • Limb data: E-MTAB-11341 (Suo, Dann et al. 2022)
  • Facial and abdominal data: E-MTAB-13024
• Skin organoid libraries:
  • Gene Expression Omnibus GSE147206 (Lee, Rabbani, Gao et al. 2020)
  • Gene Expression Omnibus GSE188936 (Lee, Rabbani, Gao et al. 2020)
  • Gene Expression Omnibus GSE231607 (Lee, Rabbani, Gao et al. 2020)

License

The code in this repository is licensed under the GNU Affero General Public License v3.0

Citation

If you use this repo, please cite it

Contact, collaboration and contributions

For any questions, please post an issue in this repository or contact by email mh32[at]sanger.ac.uk